Anti-TLK2/PKU-ALPHA antibody

Anti-TLK2/PKU-ALPHA antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to TLK2/PKU-ALPHA

IHC-P

Human TLK2 / PKU-ALPHA
Has cross-reactivity in ELISA with Human CD64
No cross-reactivity in ELISA with Human CD16a; Human CD16b; Human CD32a; Human CD32b; Mouse FCGR3

MGC44450 antibody; PKU-ALPHA antibody; RP23-456M3.2 antibody; Tlk antibody; 4933403M19Rik antibody; PKUalpha antibody; Tlk2 antibody; TLK2 antibody; HsHPK antibody; PKU-ALPHA antibody; Tlk antibody; PKUalpha antibody; PKU-alpha antibody; 4933403M19Rik antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human TLK2 / PKU-ALPHA (rh TLK2 / PKU-ALPHA; Q86UE8-1; Leu397-Asn772). TLK2 / PKU-ALPHA specific IgG was purified by Human TLK2 / PKU-ALPHA affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS with 5% trehalose

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Serine / threonine-protein kinase tousled-like 2, also known as PKU-alpha, Tousled-like kinase 2 and TLK2, is a nucleus protein which belongs to the protein kinase superfamily and Ser/Thr protein kinase family. The tousled-like kinases are an evolutionarily conserved family of proteins implicated in DNA repair, DNA replication and mitosis in metazoans and plants. Their absence from the yeasts and other eukaryotic 'microbes' suggests a specific role for them in the development of multicellular organisms. Tousled-like kinase 2 / TLK2 is widely expressed. It is present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. It is also found in adult cell lines. Tousled-like kinase 2 / TLK2 contains one protein kinase domain. Tousled-like kinase 2 / TLK2 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.

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