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Product Name
Anti-TFPI Rabbit antibody
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Description
TFPI Rabbit monoclonal antibody
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Tested applications
WB, FC, IP
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Species reactivity
Human
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human TFPI
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
FC: 1/50
IP: 1/20
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Validations
Western blot detection of TFPI in A549,HL-60,U2OS cell lysates using TFPI Rabbit mAb(1:1000 diluted).Predicted band size:35kDa.Observed band size:40-55kDa.
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Background
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"