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Product Name
Anti-TCEA1 Rabbit antibody
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Description
TCEA1 Rabbit monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
SII; TCEA; TF2S; GTF2S; TFIIS antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human TCEA1
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of TCEA1 in K562,C6,3T3 cell lysates using TCEA1 Rabbit mAb(1:1000 diluted).Predicted band size:34kDa.Observed band size:34kDa.
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Background
Swiss-Prot Acc.P23193.Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.MiscellaneousS-II binds to RNA-polymerase II in the absence of transcription.RegionsFeature keyPosition(s)Description
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"