-
Product Name
Anti-STAT4 Rabbit antibody
- Documents
-
Description
STAT4 Rabbit monoclonal antibody
-
Tested applications
WB, IHC-P, ICC/IF, FC, IP
-
Species reactivity
Human
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human STAT4
-
Clonality
Monoclonal
-
Formulation
50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/1000
IHC: 1/50
ICC/IF: 1/50
FC: 1/20
IP: 1/20
-
Validations
Western blot detection of STAT4 in Hela,A549 cell lysates using STAT4 Rabbit mAb(1:1000 diluted).Predicted band size:86kDa.Observed band size:86kDa.
-
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"