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Product Name
Anti-SPINK5/LEKTI Rabbit antibody
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Description
SPINK5/LEKTI Rabbit monoclonal antibody
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Tested applications
WB, ICC/IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
NS; NETS; LEKTI; LETKI; VAKTI antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human SPINK5
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/5000
ICC/IF: 1/20-1/100
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Validations
Western blot detection of SPINK5/LEKTI in Hela cell lysates using SPINK5/LEKTI Rabbit mAb(1:500 diluted).Predicted band size:121kDa.Observed band size:121kDa.
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Background
Swiss-Prot Acc.Q9NQ38.Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"