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Product Name
Anti-SerpinB4 / SCCA2 antibody
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Description
Rabbit monoclonal to SerpinB4 / SCCA2
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Tested applications
IHC-P
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Species reactivity
Human SerpinB4 / SCCA2
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinB4 / SCCA2 (rh SerpinB4 / SCCA2; P48594; Met1-Pro390).
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Clonality
Monoclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
IHC-P: 1-10 μg/mL
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Validations
SerpinB4 / SCCA2 Antibody, Rabbit MAb, Immunohistochemistry
Immunochemical staining of human SERPINB4 in human skin with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
SerpinB4 / SCCA2 Antibody, Rabbit MAb, Immunohistochemistry
Immunochemical staining of human SERPINB4 in human esophageal carcinoma with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
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References
- de Koning PJ, et al. (2011) Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death. PLoS One. 6(8): e22645.
- Chechlinska M, et al. (2010) Squamous cell carcinoma antigen 1 and 2 expression in cultured normal peripheral blood mononuclear cells and in vulvar squamous cell carcinoma. Tumour Biol. 31(6): 559-67.
- Shiiba M, et al. (2010) Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas. Oncol Rep. 24(1): 241-9. en, Der p 1. J Biol Chem. 279(7): 5081-7.
- Murakami A, et al. (2008) Relationship between decreased expression of squamous cell carcinoma antigen 2 and E-cadherin in primary cervical cancer lesions and lymph node metastasis. Oncol Rep. 19(1): 99-104.
- Silverman GA, et al. (1998) SCCA1 and SCCA2 are proteinase inhibitors that map to the serpin cluster at 18q21.3. Tumour Biol. 19(6): 480-7.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"