Anti-SCN2B antibody

Anti-SCN2B antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human SCN2B

ELISA, IHC-P

Human SCN2B

2810451E09Rik antibody; AI840361 antibody; beta polypeptide antibody; Gm183 antibody; neuronal voltage-gated sodium channel beta 2 subunit antibody; sodium channel antibody; sodium channel antibody; sodium channel beta 2 subunit antibody; sodium channel subunit beta-2 antibody; sodium channel subunit beta-2 antibody; type II antibody; type II antibody; UNQ326/PRO386 antibody; voltage-gated antibody; voltage-gated antibody; beta polypeptide antibody; ATFB14 antibody; Gm183 antibody; AI840361 antibody; 2810451E09Rik antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human SCN2B . SCN2B specific IgG was purified by Human SCN2B affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

SCN2B plays a key role in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which may be associated with either one or more beta-subunits. Alpha-subunits are composed for four homologous domains, each of which contains six transmembrane segments.They are responsible for action potential initiation and propagation in excitable cells, including nerve, muscle, and neuroendocrine cell types. SCN2B causes an increase in the plasma membrane surface area and in its folding into microvilli. SCN2B also interacts with TNR and may play a crucial role in clustering and regulation of activity of sodium channels at nodes of ranvier.