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Product Name
Anti-Scavenging Receptor SR-BI Rabbit antibody
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Description
Scavenging Receptor SR-BI Rabbit monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Scavenging Receptor SR-BI
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of Scavenging Receptor SR-BI in 3T3,Hela cell lysates using Scavenging Receptor SR-BI Rabbit mAb(1:1000 diluted).Predicted band size:61kDa.Observed band size:80kDa.
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Background
Swiss-Prot Acc.Q8WTV0.Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"