Anti-SCARB1 antibody

Anti-SCARB1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human SCARB1

WB, ICC/IF, IF, IP

Human SR-BI/SCARB1/CD36L1

AI120173 antibody; CD36 antibody; Cd36l1 antibody; CD36L1 antibody; CLA1 antibody; Cla1 antibody; Cla-1 antibody; CLA-1 antibody; D5Ertd460e antibody; MGC138242 antibody; mSR-BI antibody; Scarb1 antibody; SCARB1 antibody; Srb1 antibody; SR-B1 antibody; SRB1 antibody; SRBI antibody; SR-BI antibody; SR-BI antibody; CD36 antibody; Cla1 antibody; SRBI antibody; Srb1 antibody; Cla-1 antibody; Hdlq1 antibody; SR-B1 antibody; SR-BI antibody; Cd36l1 antibody; Hlb398 antibody; mSR-BI antibody; AI120173 antibody; D5Ertd460e antibody; CLA1 antibody; SRB1 antibody; CLA-1 antibody; SR-BI antibody; CD36L1 antibody; HDLQTL6 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human SR-BI/SCARB1/CD36L1 . SR-BI/SCARB1/CD36L1 specific IgG was purified by Human SR-BI/SCARB1/CD36L1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane. SCARB1 is proposed as a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells, and is involved in a wide variety of physilogical processes. As a key component in the reverse cholesterol transport pathway, SCARB1 binds high density lipoproteins (HDLs) and mediates selective cholesterol uptake by a mechanism distinct from the LDL pathway. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SCARB1 may thus serve as a useful marker that predicts variation in baseline lipid levels and postprandial lipid response. The mouse SCARB1 has been shown to exert actions in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.