Anti-S100A9 antibody

Cat.#: 141281

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Product Information

  • Product Name
    Anti-S100A9 antibody
  • Documents
  • Description
    Rabbit Polyclonal to Mouse S100A9
  • Tested applications
    ELISA, IHC-P
  • Species reactivity
    Mouse S100A9 / MRP-14
  • Alternative names
    P14 antibody; CFAG antibody; P14 antibody; 60B8Ag antibody; BEE22 antibody; L1Ag antibody; LIAG antibody; MAC387 antibody; MIF antibody; MRP14 antibody; MRP14 antibody; P14 antibody; 60B8AG antibody; AW546964 antibody; Cagb antibody; CAGB antibody; CGLB antibody; GAGB antibody; L1AG antibody; MRP-14 antibody; MRP-14 antibody; NIF antibody; S100a9 antibody; S100A9 antibody; MIF antibody; NIF antibody; CFAG antibody; L1Ag antibody; 60B8AG antibody; 60B8Ag antibody; CAGB antibody; CGLB antibody; LIAG antibody; MRP14 antibody; MAC387 antibody; Cagb antibody; GAGB antibody; L1Ag antibody; BEE22 antibody; MRP14 antibody; AW546964 antibody; p14 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Mouse S100A9 / MRP-14 . S100A9 / MRP-14 specific IgG was purified by Mouse S100A9 / MRP-14 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    ELISA: 0.1-0.2 μg/ml

    This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Mouse S100A9 / MRP-14.

    IHC-P: 0.05-1 μg/mL

  • Validations

    Mouse S100A9/MRP-14 Immunohistochemistry(IHC) 14739

    Mouse S100A9/MRP-14 Immunohistochemistry(IHC) 14739

  • Background
    S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calcium-binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"