Anti-RUVBL1 / RVB1 antibody

Anti-RUVBL1 / RVB1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to RUVBL1 / RVB1

ELISA, WB, IHC-P, IP

Human RUVBL1 / RVB1

2510009G06Rik antibody; 49 kDa TATA box-binding protein-interacting protein antibody; 49 kDa TATA box-binding protein-interacting protein antibody; 49 kDa TBP-interacting protein antibody; 49 kDa TBP-interacting protein antibody; 54 kDa erythrocyte cytosolic protein antibody; DNA helicase p50 antibody; ECP54 antibody; ECP-54 antibody; INO80 complex subunit H antibody; INO80H antibody; NMP 238 antibody; NMP238 antibody; nuclear matrix protein 238 antibody; PONTIN antibody; pontin 52 antibody; Pontin 52 antibody; Pontin52 antibody; Pontin52 antibody; RuvB (E coli homolog)-like 1 antibody; Ruvbl1 antibody; RUVBL1 antibody; ruvB-like 1 antibody; ruvB-like 1 antibody; RVB1 antibody; TAP54-alpha antibody; TATA binding protein interacting protein 49 kDa antibody; TIH1 antibody; TIP49 antibody; Tip49a antibody; TIP49A antibody; TIP60-associated protein 54-alpha antibody; RVB1 antibody; ECP54 antibody; TIP49 antibody; INO80H antibody; NMP238 antibody; PONTIN antibody; TIP49A antibody; Pontin52 antibody; Tip49a antibody; Pontin52 antibody; 2510009G06Rik antibody; TIH1 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human RUVBL1 / RVB1 (rh RUVBL1 / RVB1; Q9Y265-1; Met1-Lys456). RUVBL1 / RVB1 specific IgG was purified by Human RUVBL1 / RVB1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.; FUNCTION: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.; FUNCTION: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.; FUNCTION: Plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. Essential for cell proliferation.; FUNCTION: May be able to bind plasminogen at cell surface and enhance plasminogen activation.