Anti-RSK3/RPS6KA2 antibody

Anti-RSK3/RPS6KA2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to RSK3/RPS6KA2

IHC-P, IF, ICC/IF

Human RSK3 / RPS6KA2

90kDa antibody; HU-2 antibody; p90-RSK3 antibody; pp90rsk antibody; pp90RSK3 antibody; RP1-168L15.2 antibody; Rps6ka2 antibody; RPS6KA2 antibody; Rps6ka-rs1 antibody; Rsk3 antibody; RSK3 antibody; S6K-alpha antibody; S6K-alpha2 antibody; D17Wsu134e antibody; MAPKAPK1C antibody; p90rsk antibody; RSK antibody; RSK antibody; RSK3 antibody; p90-RSK3 antibody; pp90RSK3 antibody; MAPKAPK1C antibody; S6K-alpha antibody; S6K-alpha2 antibody; Rsk3 antibody; p90rsk antibody; pp90rsk antibody; D17Wsu134e antibody; Rps6ka-rs1 antibody; HU-2 antibody; 90kDa antibody

Rabbit IgG

Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human RSK3 / RPS6KA2, and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Ribosomal protein S6 kinase alpha-2, also known as 90 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA2 / RSK-3 is expressed in many tissues. Highest expression is in lung and skeletal muscle. The expression of RPS6KA2 reduced proliferation, caused G1 arrest, increased apoptosis, reduced levels of phosphorylated extracellular signal-regulated kinase and altered other cell cycle proteins. RPS6KA2 / RSK-3 contains one AGC-kinase C-terminal domain and two protein kinase domains. It forms a complex with either ERK1 or ERK2 in quiescent cells. It transiently dissociates following mitogenic stimulation. RPS6KA2 / RSK-3 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 are involved in several pathways central to the carcinogenic process, including regulation of cell growth, insulin, and inflammation.