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Product Name
Anti-REA Rabbit antibody
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Description
REA Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
BAP; REA; p22; hBAP; Bap37; BCAP37; PNAS-141 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human REA
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/2000-1/10000
IHC: 1/50
ICC/IF: 1/50
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Validations
Immunocytochemistry of REA(green) in Hela cells using REA Rabbit pAb at dilution 1/50, and DAPI(blue)
Western blot detection of REA in K562,Rat Brain,C6,3T3,Hela cell lysates using REA Rabbit pAb(1:1000 diluted).Predicted band size:33kDa.Observed band size:33kDa.
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Background
Swiss-Prot Acc.Q99623.Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases . Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"