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Product Name
Anti-RAP1A/RAP1B Rabbit antibody
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Description
RAP1A/RAP1B Rabbit polyclonal antibody
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Tested applications
WB, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human RAP1A/B
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/2000-1/10000
FC: 1/20
IP: 1/20
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Validations
Western blot detection of RAP1A/B in K562,Rat Brain,C6,3T3,Hela cell lysates using RAP1A/B Rabbit pAb(1:1000 diluted).Predicted band size:21kDa.Observed band size:21kDa.
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Background
Swiss-Prot Acc.P61224.GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"