-
Product Name
Anti-PSMA4 Rabbit antibody
- Documents
-
Description
PSMA4 Rabbit polyclonal antibody
-
Tested applications
WB, IHC-P, ICC/IF, IP
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
HC9; PSC9; HsT17706 antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human PSMA4
-
Clonality
Polyclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
-
Applications
WB: 1/1000-1/5000
IHC: 1/100
ICC/IF: 1/100
IP: 1/50
-
Validations
Western blot detection of PSMA4 in K562,C6,3T3,Hela cell lysates using PSMA4 Rabbit pAb(1:1000 diluted).Predicted band size:30kDa.Observed band size:30kDa.
Immunohistochemistry of PSMA4 in paraffin-embedded Human tonsil using PSMA4 Rabbit pAb at dilution 1/50
-
Background
Swiss-Prot Acc.P25789.Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"