Anti-Prohibitin (5H7) Mouse antibody
Prohibitin (5H7) Mouse monoclonal antibody
WB, IHC-P, ICC/IF, FC
Human, Mouse, Rat, Monkey
Antigen: Purified recombinant fragment of human PHB expressed in E. Coli.
Ascitic fluid containing 0.03% sodium azide.
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
ICC: 1/200 - 1/1000
FC: 1/200 - 1/400
Western blot detection of Prohibitin in C6,COS7,3T3 and Hela cell lysates using Prohibitin mouse mAb (dilution 1:1000).Predicted band size:30 Kda.Observed band size:30KDa.
Swiss-Prot Acc.P35232.Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"