Anti-PROCR antibody

Anti-PROCR antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Monoclonal to Mouse PROCR

FCM

Mouse Epcr/PROCR

CCCA antibody; EPCR antibody; CCD41 antibody; Ccca antibody; Epcr antibody; Ccd41 antibody; AI325044 antibody; AI325044 antibody; bA42O4.2 antibody; CCCA antibody; Ccca antibody; Ccd41 antibody; CCD41 antibody; CD201 antibody; EPCR antibody; Epcr antibody; MGC23024 antibody; RP23-388H13.2 antibody

Rabbit IgG

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Epcr/PROCR and conjugated with PE under optimum conditions, the unreacted PE was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found maily near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depend on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other.