Anti-PRMT6 (2C3) Mouse antibody

Anti-PRMT6 (2C3) Mouse antibody

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• Material Safety Data Sheets (MSDS)

PRMT6 (2C3) Mouse monoclonal antibody

WB, IHC-P, ICC/IF

Human

ANM6_HUMAN;Chromobox protein homolog 7;FLJ10559;FLJ51477;Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 6;Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;Histone-arginine N-methyltransferase PRMT6;HMT1 hnRN antibody

Mouse IgG1

Antigen: Purified recombinant human PRMT6 protein fragments expressed in E.coli.

Monoclonal

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol

Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Swiss-Prot Acc.Q96LA8.The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.