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Product Name
Anti-PRMT1 (4E9) Mouse antibody
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Description
PRMT1 (4E9) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
ANM 1;ANM1;ANM1_HUMAN;complete cds;HCP 1;HCP1;Heterogeneous nuclear ribonucleoprotein methyltransferase 1 like 2;Heterogeneous nuclear ribonucleoproteins methyltransferase like 2;Heterogeneous nuclear ribonucleoproteins methyltransferase like2;Histone-arg antibody
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Isotype
Mouse IgG2b
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Preparation
Antigen: Purified recombinant human PRMT1 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
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Validations
Western blot detection of PRMT1 in Hela,A549 and SW480 cell lysates using PRMT1 mouse mAb (1:1000 diluted).Predicted band size:42KDa.Observed band size:42KDa.
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Background
Swiss-Prot Acc.Q99873.Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"