Anti-PRKAR1A antibody

Anti-PRKAR1A antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human PRKAR1A

WB, ELISA, IP

Human PRKAR1A / PRKAR1 / PKR1

protein kinase antibody; cAMP-dependent antibody; regulatory antibody; type I antibody; alpha antibody; PRKAR1A antibody; ACRDYS1 antibody; ADOHR antibody; CAR antibody; CNC antibody; CNC1 antibody; PKR1 antibody; PPNAD1 antibody; PRKAR1 antibody; TSE1 antibody; cAMP-dependent protein kinase regulatory subunit RIalpha antibody; cAMP-dependent protein kinase type I-alpha regulatory chain antibody; cAMP-dependent protein kinase type I-alpha regulatory subunit antibody; protein kinase A type 1a regulatory subunit antibody; tissue specific extinguisher 1 antibody; protein kinase antibody; Prkar1a antibody; RP23-80J21.2 antibody; 1300018C22Rik antibody; RIalpha antibody; Tse-1 antibody; Tse1 antibody; cAMP-dependent protein kinase type I-alpha regulatory subunit antibody; protein kinase antibody; cAMP dependent regulatory antibody; type 1 antibody; alpha antibody; CNC antibody; CNC1 antibody; PKR1 antibody; TSE1 antibody; ADOHR antibody; PPNAD1 antibody; PRKAR1 antibody; ACRDYS1 antibody; Tse1 antibody; Tse-1 antibody; RIalpha antibody; 1300018C22Rik antibody; RIIA antibody; CAR antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human PRKAR1A / PRKAR1 / PKR1 . PRKAR1A / PRKAR1 / PKR1 specific IgG was purified by Human PRKAR1A / PRKAR1 / PKR1 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

PRKAR1A, also known as PRKAR1 and PKR1, is one of the regulatory subunits of cAMP-dependent protein kinase A (PKA). PKA can be activated by cAMP. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating PKA, which transduces the signal throughphosphorylation of different target proteins. The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of PKA have been identified in humans. PRKAR1A was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids Three alternatively spliced transcript variants encoding the same protein have been observed.