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Product Name
Anti-PLS3 antibody
- Documents
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Description
Rabbit Polyclonal to Human PLS3
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Tested applications
ELISA, IP
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Species reactivity
Human PLS3 / Plastin 3
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Alternative names
BMND18 antibody; T-plastin antibody; AI115446 antibody; AL024105 antibody; T-fimbrin antibody; plastin 3 antibody; PLS3 antibody; T-plastin antibody; T fimbrin antibody; plastin 3 (T-isoform) antibody; Pls3 antibody; RP23-162M7.1 antibody; AI115446 antibody; AL024105 antibody; T-fimbrin antibody; T-plastin antibody; plastin 3 antibody; T antibody; plastin-3 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human PLS3 / Plastin 3 . PLS3 / Plastin 3 specific IgG was purified by Human PLS3 / Plastin 3 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA: 0.1-0.2 μg/ml
This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Human PLS3 / Plastin 3.
IP: 1-4 μl/mg of lysate
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Validations
Human PLS3 / Plastin 3 Immunoprecipitation(IP) 14729
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Background
PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). PLS3 contains 2 actin-binding domains, 4 CH (calponin-homology) domains and 2 EF-hand domains. It is expressed in a variety of organs, including muscle, brain, uterus and esophagus.
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