Anti-PLBD2 antibody

Anti-PLBD2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human PLBD2

WB, IHC-P, IP

Human PLBD2

P76 antibody; AU019810 antibody; 1300012G16Rik antibody; P76 antibody; phospholipase B domain containing 2 antibody; PLBD2 antibody; P76 antibody; 76 kDa protein antibody; LAMA-like protein 2 antibody; PLB homolog 2 antibody; lamina ancestor homolog 2 antibody; mannose-6-phosphate protein associated protein p76 antibody; phospholipase B domain-containing protein 2 antibody; phospholipase B-like 2 32 kDa form antibody; phospholipase B-like 2 45 kDa form antibody; putative phospholipase B-like 2 antibody; phospholipase B domain containing 2 antibody; Plbd2 antibody; 1300012G16Rik antibody; AU019810 antibody; P76 antibody; 66.3 kDa protein antibody; 76 kDa protein antibody; LAMA-like protein 2 antibody; lamina ancestor homolog 2 antibody; phospholipase B domain-containing protein 2 antibody; putative phospholipase B-like 2 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human PLBD2 . PLBD2 specific IgG was purified by Human PLBD2 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

PLBD2 localizes to the lysosome, as its absence could plausibly lead to a serious yet unrecognized lysosomal storage disease. PLBD1 and PLBD2 are semi-orphans in the sense of being probable phospholipases of B class but with uncertain physiological substrates and thus functionalities. PLBD1 and PLBD2 constitute a small gene family (sequence homology class) within vertebrates though one that occurs expanded in some early diverging eukaryotes. PLBD2 presents a special difficulty in that a sequence of post-translational steps are apparently necessary for its activation. Without these, potential substrates can hardly be assayed. These steps include removal of the signal peptide, mannosylation appropriate to the lysosome targeting receptor, and self-catalytic proteolytic activation to expose the substrate binding site as this becomes appropriate.