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Product Name
Anti-PEBP1/RKIP antibody
- Documents
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Description
Rabbit polyclonal to PEBP1/RKIP
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Tested applications
ELISA, WB, IP
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Species reactivity
Human PEBP1
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Alternative names
PBP antibody; HCNP antibody; HCNPpp antibody; HEL-210 antibody; HEL-S-34 antibody; PBP antibody; PEBP antibody; PEBP-1 antibody; RKIP antibody; HCNP antibody; Pbp antibody; Pbp1 antibody; Pbpr antibody; Rkip antibody; PBP antibody; HCNP antibody; PEBP antibody; RKIP antibody; HCNPpp antibody; PEBP-1 antibody; HEL-210 antibody; HEL-S-34 antibody; HCNP antibody; Pbp1 antibody; Pbpr antibody; Rkip antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human PEBP1 (rh PEBP1; NP_002558.1; Met1-Lys187). PEBP1 specific IgG was purified by Human PEBP1 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 2-10 μg/ml
ELISA:0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human PEBP1. The detection limit for Human PEBP1 is < 0.039 ng/well.
IP: 0.5-2 μg/mg of lysate
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Validations
PEBP1 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
PEBP1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation
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Background
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity). Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation..; FUNCTION: HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"