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Product Name
Anti-PCPTP1/PTPRQ Rabbit antibody
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Description
PCPTP1/PTPRQ Rabbit monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human PCPTP1
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000
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Validations
Western blot detection of PCPTP1/PTPRQ in Rat Brain lysates using PCPTP1/PTPRQ Rabbit mAb(1:1000 diluted).Predicted band size:74kDa.Observed band size:74kDa.
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Background
Swiss-Prot Acc.Q15256.Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus .
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"