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Product Name
Anti-PCBP2/hnRNP E2 Rabbit antibody
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Description
PCBP2/hnRNP E2 Rabbit monoclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
HNRPE2; HNRNPE2; hnRNP-E2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human PCBP2
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000
1:100
1:50
1:20
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Validations
Western blot detection of PCBP2/hnRNP E2 in C6,3T3 cell lysates using PCBP2/hnRNP E2 Rabbit mAb(1:1000 diluted).Predicted band size:39kDa.Observed band size: 35-45kDa.
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Background
Swiss-Prot Acc.Q15366.Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"