-
Product Name
Anti-PAX6 Rabbit antibody
- Documents
-
Description
PAX6 Rabbit monoclonal antibody
-
Tested applications
WB, IHC-P, FC
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
AN; AN2; FVH1; MGDA; WAGR; ASGD5; D11S812E antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human PAX6
-
Clonality
Monoclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
1:1000-1:5000
1:20-1:100
1:100-1:500
-
Validations
Western blot detection of PAX6 in Rat Brain lysates using PAX6 Rabbit mAb(1:1000 diluted).Predicted band size:47kDa.Observed band size:47kDa.
-
Background
Swiss-Prot Acc.P26367.Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains . Isoform 5a appears to function as a molecular switch that specifies target genes.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"