-
Product Name
Anti-pan Cadherin Rabbit antibody
- Documents
-
Description
pan Cadherin Rabbit monoclonal antibody
-
Tested applications
WB, IHC-P, ICC/IF, FC, IP
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
CDHP; HJMD; PCAD antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human pan Cadherin
-
Clonality
Monoclonal
-
Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/5000
IHC: 1/20
ICC/IF: 1/20
FC: 1/20
IP: 1/20
-
Validations
Western blot detection of pan Cadherin in Hela,CHO-K1,C6,Rat Brain lysates using pan Cadherin Rabbit mAb(1:500 diluted).Predicted band size:100kDa.Observed band size:130-150kDa.
-
Background
Swiss-Prot Acc.P12830.Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"