-
Product Name
Anti-p60 katanin Rabbit antibody
- Documents
-
Description
p60 katanin Rabbit monoclonal antibody
-
Tested applications
WB, ICC/IF
-
Species reactivity
Human
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human p60 katanin
-
Clonality
Monoclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
1:1000-1:5000
1:20
-
Validations
Western blot detection of p60 katanin in K562,Hela cell lysates using p60 katanin Rabbit mAb(1:1000 diluted).Predicted band size:56kDa.Observed band size:56kDa.
-
Background
Swiss-Prot Acc.O75449.Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"