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Product Name
Anti-Ntrk2 antibody
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Description
Rabbit monoclonal antibody to Ntrk2
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Tested applications
WB
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Species reactivity
Mouse, Rat
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Alternative names
Tkr antibody; trk antibody; Tkrb antibody; trkB antibody; trk-B antibody; GP145-TrkB/GP95-TrkB antibody
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Isotype
IgG
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Preparation
This antigen of this antibody was recombinant protein within human trkb aa 100-450.
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
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Applications
WB: 1:500-1:2,000
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Validations
Fig1:; Western blot analysis of TrkB on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody ( 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.; Positive control:; Lane 1: mouse brain tissue lysate; Lane 2: mouse cerebellum tissue lysate; Lane 3: rat cerebellum tissue lysate
- Background
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References
- Wang X. et. al. A tropomyosin receptor kinase family protein, NTRK2 is a potential predictive biomarker for lung adenocarcinoma. PeerJ. 2019 Jun
- Cocco E. et. al. NTRK fusion-positive cancers and TRK inhibitor therapy. Nat Rev Clin Oncol. 2018 Dec
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"