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Product Name
Anti-NRG3 Rabbit antibody
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Description
NRG3 Rabbit monoclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
HRG3; pro-NRG3 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human NRG3
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000-1:5000
1:20
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Validations
Western blot detection of NRG3 in K562,Rat Brain lysates using NRG3 Rabbit mAb(1:1000 diluted).Predicted band size:78kDa.Observed band size:55kDa.
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Background
Swiss-Prot Acc.P56975.Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"