Anti-NLGN3 antibody

Cat.#: 142364

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Product Information

  • Product Name
    Anti-NLGN3 antibody
  • Documents
  • Description
    Rabbit Monoclonal to Human NLGN3
  • Tested applications
    FCM
  • Species reactivity
    Human Neuroligin 3 / NLGN3
  • Alternative names
    A230085M13Rik antibody; Nlgn3 antibody; RP23-440J15.4 antibody; HNL3 antibody; HNL3 antibody; KIAA1480 antibody; Neuroligin 3 antibody; Neuroligin 3 antibody; NL3 antibody; HNL3 antibody; NL3 antibody; HNL3 antibody; A230085M13Rik antibody; NLGN3 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained from a rabbit immunized with purified, recombinant Human Neuroligin 3 / NLGN3 .
  • Clonality
    Monoclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    FCM: 0.5-2 μg/Test

  • Validations

    Neuroligin 3 / NLGN3 Antibody, Rabbit MAb, Flow Cytometry

    Neuroligin 3 / NLGN3 Antibody, Rabbit MAb, Flow Cytometry

  • Background
    Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface proteins that interact with neurexins (beta-Nxs), another class of neuronal cell-surface proteins, one of each class functioning together in synapse formation. Neuroligins control the formation and functional balance of excitatory and inhibitory synapses in hippocampal neurons. NLGN1 and NLGN2 isoforms are concentrated at glutamatergic and GABAergic synapses, respectively, but the cellular expression and synaptic localization of the endogenous. NLGN3 was enriched in brain, where NLGN3 protein levels increased during postnatal development, coinciding with the peak of synaptogenesis. The NLGN3 is a synaptic adhesion molecule that is a shared component of glutamatergic and GABAergic synapses. Mutations in NLGN3 gene may be associated with autism and Asperger syndrome.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"