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Product Name
Anti-Muscarinic Acetylcholine Receptor 2/CM2 Rabbit antibody
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Description
Muscarinic Acetylcholine Receptor 2/CM2 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
HM2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Muscarinic Acetylcholine Receptor 2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000-1/5000
IHC: 1/20-1/100
IP: 1/20-1/50
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Validations
Western blot detection of Muscarinic Acetylcholine Receptor 2/CM2 in K562,C6,Hela cell lysates using Muscarinic Acetylcholine Receptor 2/CM2 Rabbit pAb(1:1000 diluted).Predicted band size:52kDa.Observed band size:52kDa.
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Background
Swiss-Prot Acc.P08172.The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"