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Product Name
Anti-MIF Rabbit antibody
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Description
MIF Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
GIF; GLIF; MMIF antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human MIF
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
ICC/IF: 1/20
FC: 1/100
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Validations
Western blot detection of MIF in C6,3T3 cell lysates using MIF Rabbit pAb(1:1000 diluted).Predicted band size:13kDa.Observed band size:13kDa.
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Background
Swiss-Prot Acc.P14174.Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"