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Product Name
Anti-MEK3 Rabbit antibody
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Description
MEK3 Rabbit monoclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human MEK3
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000
ICC/IF: 1/50
FC: 1/100
IP: 1/20
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Validations
Western blot detection of MEK3 in C6,3T3,Hela cell lysates using MEK3 Rabbit mAb(1:1000 diluted).Predicted band size:39kDa.Observed band size: 38-40kDa.
Immunocytochemistry of MEK3(green) in Hela cells using MEK3 Rabbit mAb at dilution 1/50, and DAPI(blue)
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Background
Swiss-Prot Acc.P46734.Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"