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Anti-LPP (6F6) Mouse antibody

Cat.#: 168424

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Product Information

  • Product Name
    Anti-LPP (6F6) Mouse antibody
  • Documents
  • Description
    LPP (6F6) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, IP
  • Species reactivity
    Human, Mouse, Monkey, Hamster
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human LPP expressed in E. Coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    IHC: 1/200 - 1/1000

    ICC: 1/200 - 1/1000

    ELISA: 1/10000

  • Validations

    Confocal immunofluorescence analysis of COS cells using LPP mouse mAb (green). Red: Actin filaments have been labeled using DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

    Confocal immunofluorescence analysis of COS cells using LPP mouse mAb (green). Red: Actin filaments have been labeled using DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

    Immunohistochemical analysis of paraffin-embedded human vessels tissues using LPP mouse mAb.

    Immunohistochemical analysis of paraffin-embedded human vessels tissues using LPP mouse mAb.

    Confocal immunofluorescence analysis of Hela cells using LPP mouse mAb (green). Red: Actin filaments have been labeled using DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

    Confocal immunofluorescence analysis of Hela cells using LPP mouse mAb (green). Red: Actin filaments have been labeled using DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

    Immunohistochemical analysis of paraffin-embedded human small intestine using LPP mouse mAb with DAB staining.

    Immunohistochemical analysis of paraffin-embedded human small intestine using LPP mouse mAb with DAB staining.

    Western blot detection of LPP in A549,MCF7,C6 and Hela cell lysates using LPP mouse mAb (1:5000 diluted).Predicted band size:66KDa.Observed band size:75KDa.

    Western blot detection of LPP in A549,MCF7,C6 and Hela cell lysates using LPP mouse mAb (1:5000 diluted).Predicted band size:66KDa.Observed band size:75KDa.

    Immunoprecipitation analysis of Hela cell lysates using LPP (6F6) Mouse mAb.

    Immunoprecipitation analysis of Hela cell lysates using LPP (6F6) Mouse mAb.

  • Background
    Swiss-Prot Acc.Q93052.LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxyterminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentiallytranslocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"