Anti-KDM4B/JMJD2B Rabbit antibody

Cat.#: 167384

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-KDM4B/JMJD2B Rabbit antibody
  • Documents
  • Description
    KDM4B/JMJD2B Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    JMJD2B; TDRD14B antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human KDM4B/JMJD2B
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IHC: 1/20

    ICC/IF: 1/200

    FC: 1/200

  • Validations

    Immunocytochemistry of KDM4B/JMJD2B(green) in Hela cells using KDM4B/JMJD2B Rabbit pAb at dilution 1/50, and DAPI(blue)

    Immunocytochemistry of KDM4B/JMJD2B(green) in Hela cells using KDM4B/JMJD2B Rabbit pAb at dilution 1/50, and DAPI(blue)

    Immunohistochemistry of KDM4B/JMJD2B in paraffin-embedded Human lung cancer tissue using KDM4B/JMJD2B Rabbit pAb at dilution 1/20

    Immunohistochemistry of KDM4B/JMJD2B in paraffin-embedded Human lung cancer tissue using KDM4B/JMJD2B Rabbit pAb at dilution 1/20

    Western blot detection of KDM4B in 293,COS7 cell lysates using KDM4B/JMJD2B Rabbit pAb(1:1000 diluted).Predicted band size:122KDa.Observed band size:150KDa.

    Western blot detection of KDM4B in 293,COS7 cell lysates using KDM4B/JMJD2B Rabbit pAb(1:1000 diluted).Predicted band size:122KDa.Observed band size:150KDa.

  • Background
    Swiss-Prot Acc.O94953.Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"