-
Product Name
Anti-KAT13D/CLOCK Mouse antibody
- Documents
-
Description
KAT13D/CLOCK Mouse monoclonal antibody
-
Tested applications
ICC/IF
-
Species reactivity
Human
-
Isotype
Mouse IgG1
-
Preparation
Antigen: Purified recombinant fragment of human CLOCK expressed in E. Coli.
-
Clonality
Monoclonal
-
Formulation
Ascitic fluid containing 0.03% sodium azide.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
ICC: 1/200 - 1/1000
ELISA: 1/10000
-
Validations
Immunofluorescence analysis of Hela cells using CLOCK mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Western blot analysis using CLOCK mouse mAb against CLOCK(AA: 200-465)-hIgGFc transfected HEK293 cell lysate.
-
Background
Swiss-Prot Acc.O15516.This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
-
References
- CLOCK interacts with RANBP9 and is involved in alternative splicing in spermatogenesis
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"