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Product Name
Anti-JAK1 (7B1) Mouse antibody
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Description
JAK1 (7B1) Mouse monoclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human, Rat
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Alternative names
JAK 1; JAK 1A; JAK 1B; JAK-1; JAK1; JAK1_HUMAN; JAK1A; JAK1B; Janus kinase 1 (a protein tyrosine kinase); Janus kinase 1; JTK3; Tyrosine protein kinase JAK 1; Tyrosine protein kinase JAK1; Tyrosine-protein kinase JAK1. antibody
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Isotype
Mouse IgG1
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Preparation
Antigen: Purified recombinant human Jak1 protein fragments expressed in E.coli.
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Clonality
Monoclonal
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Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500
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Validations
Immunoprecipitation analysis of Hela cell lysates using Jak1 mouse mAb (168126). Jak1 mouse mAb (200622-8B8) was used for the western blot analysis (1:500 diluted)
Western blot analysis of extracts from PC12,C6,Ramos and Jurkat cell lysates using Jak1 mouse mAb (1:500 diluted).Predicted band size:130kDa.Observed band size:130kDa.
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Background
Swiss-Prot Acc.P23458.Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
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References
- 6-Hydroxy-3-O-methyl-kaempferol 6-O-glucopyranoside potentiates the anti-proliferative effect of interferon α/β by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"