Anti-IKB beta Rabbit antibody

Cat.#: 167465

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-IKB beta Rabbit antibody
  • Documents
  • Description
    IKB beta Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, IP
  • Species reactivity
    Human
  • Alternative names
    IKBB; TRIP9 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human IKB beta
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IHC: 1/50

    ICC/IF: 1/50

    IP: 1/20

  • Validations

    Western blot detection of IKB beta in K562,3T3,Hela cell lysates using IKB beta Rabbit pAb(1:1000 diluted).Predicted band size:38kDa.Observed band size:48kDa.

    Western blot detection of IKB beta in K562,3T3,Hela cell lysates using IKB beta Rabbit pAb(1:1000 diluted).Predicted band size:38kDa.Observed band size:48kDa.

  • Background
    Swiss-Prot Acc.Q15653.Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"