Anti-Histone H2B Rabbit antibody

Cat.#: 167364

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-Histone H2B Rabbit antibody
  • Documents
  • Description
    Histone H2B Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Histone H2B
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/5000

    IHC: 1/20

    FC: 1/20

    IP: 1/20

  • Validations

    Western blot detection of Histone H2B in K562,C6,3T3,Hela cell lysates using Histone H2B Rabbit pAb(1:1000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

    Western blot detection of Histone H2B in K562,C6,3T3,Hela cell lysates using Histone H2B Rabbit pAb(1:1000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

    Immunohistochemistry of Histone H2B in paraffin-embedded Human colon cancer tissue using Histone H2B Rabbit pAb at dilution 1/20

    Immunohistochemistry of Histone H2B in paraffin-embedded Human colon cancer tissue using Histone H2B Rabbit pAb at dilution 1/20

  • Background
    Swiss-Prot Acc.O60814.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"