-
Product Name
Anti-Histone H2A.Z Rabbit antibody
- Documents
-
Description
Histone H2A.Z Rabbit polyclonal antibody
-
Tested applications
WB
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
H2AZ; H2A.z; H2A/z; H2A.Z-1 antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human Histone H2A.Z
-
Clonality
Polyclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
-
Applications
WB: 1/1000
-
Validations
Western blot detection of Histone H2A.Z in K562,C6,3T3 cell lysates using Histone H2A.Z Rabbit pAb(1:1000 diluted).Predicted band size:14kDa.Observed band size:14kDa.
-
Background
Swiss-Prot Acc.P0C0S5.Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"