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Product Name
Anti-HA antibody
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Description
Mouse monoclonal to HA
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Tested applications
MN, HI
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Species reactivity
Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin / HA
Has cross-reactivity with H10N3 (A/duck/Hong Kong/786/1979) Hemagglutinin (500502)/ H10N8 (A/duck/Guangdong/E1/2012) Hemagglutinin (504315)
No cross-reactivity with H10N3 (A/mallard/Minnesota/Sg-00194/2007) Hemagglutinin (503960) in ELISA assay. -
Alternative names
ha antibody; ihj antibody; sph antibody; nmf4 antibody; Spna1 antibody; Spna-1 antibody; AF093576 antibody; AI451697 antibody; CTLO antibody; HAMSV antibody; HRAS1 antibody; RASH1 antibody; p21ras antibody; C-H-RAS antibody; H-RASIDX antibody; C-BAS/HAS antibody; C-HA-RAS1 antibody
- Immunogen
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Isotype
Mouse (varialbe region) / Human (kappa / IgG1 constant)
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Preparation
It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin / HA. The antibody was produced using recombinant antibody technology.
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Clonality
Monoclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
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Applications
Hemagglutinin Inhibition (HI) - This H10N3 HA protein Neutralizing Antibody can block the binding of the recombinant H10N8 HA protein to sialic acid and inhibit the hemagglutinin activity of recombinant H10N8 HA protein. The HI titer is 0.1-0.4 µg/mL When 1 unit of H10N8 HA protein added.
Microneutralizaiton (MN) - The influenza A H10N8 HA Neutralizing Antibody can effectively neutralize the H10N8 pseduotype virus which contain HIV backbone and H10N8 HA protein from infecting 293FT cells. -
Validations
Influenza A H10N8 Hemagglutinin / HA Neutralizing Antibody
The neutralization activity of H10N8 HA protein antibody is Measured by Microneutralization test in vitro. The pseudovirus microneutralizaiton (MN) test was performed on 293FT cells infected with H10N8 (A/Jiangxi-Donghu/346/2013) pseudovirus under the treatment of serial dilution of Neutralizing Antibody. The infection with high titer H10N8 pseduotype virus is inhibited completely under 1 µg/mL influenza A H10N8 HA Neutralizing Antibody (Catalog 40359-mh001).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"