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  • Anti-Glutaminase C Rabbit antibody

Anti-Glutaminase C Rabbit antibody

Cat.#: 168897

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-Glutaminase C Rabbit antibody
  • Documents
  • Description
    Glutaminase C Rabbit monoclonal antibody
  • Tested applications
    WB, ICC/IF, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    GAC; GAM; KGA; GLS1; AAD20 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human Glutaminase C
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:1000

    1:50

    1:50

    1:20

  • Validations

    Western blot detection of Glutaminase in K562,3T3,Hela cell lysates using Glutaminase Rabbit mAb(1:1000 diluted).Predicted band size:74kDa.Observed band size:68kDa.

    Western blot detection of Glutaminase in K562,3T3,Hela cell lysates using Glutaminase Rabbit mAb(1:1000 diluted).Predicted band size:74kDa.Observed band size:68kDa.

  • Background
    Swiss-Prot Acc.O94925.Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.CautionIsoform 3 is predicted to be expressed at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay (PubMed:14759258), but has been shown to be well expressed (PubMed:17940881 and PubMed:11015561) and the encoded protein is detected in mitochondria (PubMed:22228304).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"