Anti-Glutaminase C Rabbit antibody
Glutaminase C Rabbit monoclonal antibody
WB, ICC/IF, FC, IP
Human, Mouse, Rat
GAC; GAM; KGA; GLS1; AAD20 antibody
Antigen: Recombinant protein of human Glutaminase C
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
Western blot detection of Glutaminase in K562,3T3,Hela cell lysates using Glutaminase Rabbit mAb(1:1000 diluted).Predicted band size:74kDa.Observed band size:68kDa.
Swiss-Prot Acc.O94925.Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.CautionIsoform 3 is predicted to be expressed at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay (PubMed:14759258), but has been shown to be well expressed (PubMed:17940881 and PubMed:11015561) and the encoded protein is detected in mitochondria (PubMed:22228304).
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