Anti-Glucose 6 Phosphate Dehydrogenase (2H7) Mouse antibody

Cat.#: 168348

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Product Information

  • Product Name
    Anti-Glucose 6 Phosphate Dehydrogenase (2H7) Mouse antibody
  • Documents
  • Description
    Glucose 6 Phosphate Dehydrogenase (2H7) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P, FC
  • Species reactivity
    Human
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human G6PD expressed in E. Coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    IHC: 1/200 - 1/1000

    FC: 1/200 - 1/400

    ELISA: 1/10000

  • Validations

    Western blot detection of Glucose 6 Phosphate Dehydrogenase in MCF7,Jurkat and Hela cell lysates using Glucose 6 Phosphate Dehydrogenase mouse mAb (dilution 1:500).Predicted band size:59 Kda.Observed band size:59KDa.

    Western blot detection of Glucose 6 Phosphate Dehydrogenase in MCF7,Jurkat and Hela cell lysates using Glucose 6 Phosphate Dehydrogenase mouse mAb (dilution 1:500).Predicted band size:59 Kda.Observed band size:59KDa.

  • Background
    Swiss-Prot Acc.P11413.This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"