Anti-FES antibody

Anti-FES antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human FES

ELISA, IHC-P, ICC/IF, IF

Human FES/Feline sarcoma oncogene

Fes antibody; FES antibody; FPS antibody; AI586313 antibody; FPS antibody; FPS antibody; c-fes antibody; AI586313 antibody; BB137047 antibody; FPS antibody; BB137047 antibody; c-fes antibody; Feline sarcoma oncogene antibody; Feline sarcoma oncogene antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human FES/Feline sarcoma oncogene . FES/Feline sarcoma oncogene specific IgG was purified by Human FES/Feline sarcoma oncogene affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains one FCH domain, one protein kinase domain and one SH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-60. The nuclear localization is confirmed by immunocytochemistry of neutrophils. FES has been implicated in granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and erythropoietin signal transduction. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. FES is also involved in normal hematopoiesis. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia.