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Product Name
Anti-ENSA Rabbit antibody
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Description
ENSA Rabbit polyclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
ARPP-19e antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human ENSA
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000-1/5000
FC: 1/20
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Validations
Western blot detection of ENSA in Rat Brain,C6,3T3,Hela cell lysates using ENSA Rabbit pAb(1:1000 diluted).Predicted band size:13kDa.Observed band size:15kDa.
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Background
Swiss-Prot Acc.O43768.Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase . Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"