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Product Name
Anti-ELMO1 Rabbit antibody
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Description
ELMO1 Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
CED12; CED-12; ELMO-1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human ELMO1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/5000
ICC/IF: 1/50
FC: 1/20
IP: 1/20
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Validations
Western blot detection of ELMO1 in Rat Brain,C6,3T3 cell lysates using ELMO1 Rabbit pAb(1:1000 diluted).Predicted band size:84kDa.Observed band size:84kDa.
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Background
Swiss-Prot Acc.Q92556.Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"