Anti-EIF5 antibody

Anti-EIF5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human EIF5

ELISA, IHC-P, ICC/IF, IF

Human EIF-5A/EIF5

EIF-5 antibody; EIF-5A antibody; D12Ertd549e antibody; 2810011H21Rik antibody; 2810011H21Rik antibody; D12Ertd549e antibody; EIF-5 antibody; eIF-5 antibody; EIF-5A antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human EIF-5A/EIF5 . EIF-5A/EIF5 specific IgG was purified by Human EIF-5A/EIF5 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiation complex. In protein synthesis initiation, eIF2 functions in its GTP-bound state to deliver initiator methionyl-tRNA to the small ribosomal subunit and is necessary for protein synthesis in all cells. EIF-5A stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI). EIF-5A also interacts with eIF1 and eIF3 and binds the eIF2-GTP/Met-tRNA ternary complex along with the 40S ribosome subunit.