Anti-DUSP3 antibody

Anti-DUSP3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human DUSP3

WB, ELISA, IP

Human DUSP3/VHR

2210015O03Rik antibody; 5031436O03Rik antibody; Dusp3 antibody; DUSP3 antibody; RP23-398F7.3 antibody; T-DSP11 antibody; VHR antibody; VHR antibody; VHR antibody; VHR antibody; T-DSP11 antibody; 2210015O03Rik antibody; 5031436O03Rik antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human DUSP3/VHR . DUSP3/VHR specific IgG was purified by Human DUSP3/VHR affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. Unlike typical DUSPs, VHR lacks mitogen-activated protein kinase (MAPK)-binding domain, and shows poor activity against MAPKs. VHR often act on bisphosphorylated protein substrates, it displays a strong preference for dephosphorylating phosphotyrosine residues over phosphothreonine residues. VHR has been identified as a novel regulator of extracellular regulated kinases (ERKs). VHR is responsible for the rapid inactivation of ERK following stimulation and for its repression in quiescent cells. VHR is a negative regulator of the Erk and Jnk pathways in T cells and, therefore, may play a role in aspects of T lymphocyte physiology that depend on these kinases.