Anti-DPP7 antibody

Anti-DPP7 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human DPP7

IHC-P

Human DPP7 / DPPII / DPP2

Dpp2 antibody; DPP2 antibody; DPP7 / DPPII / DPP2 antibody; DPP7 / DPPII / DPP2 antibody; DPPII antibody; DPPII antibody; QPP antibody; QPP antibody; RP23-47P18.2 antibody; Dpp2 antibody; QPP antibody; DPP2 antibody; DPPII antibody; QPP antibody; Dpp2 antibody; DPPII antibody

Rabbit IgG

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human DPP7 / DPPII / DPP2, and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis.